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AI-assisted reporting, human-reviewed. Every claim sourced and graded. Not medical advice.

© 2026 variis · Singapore · Australia

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  3. Personalised supplement protocol (biomarker-guided stack)

Protocol

Personalised supplement protocol (biomarker-guided stack)

targeted supplementation · supplement prescription · nutraceutical protocol · biomarker-guided supplementation · personalised stack

The bundled offering has no outcome trials. There is no published RCT testing whether biomarker-guided supplement selection, as a strategy, improves mortality, morbidity, or any validated healthspan endpoint versus standard care or versus untargeted supplementation. Correcting a genuine, measured deficiency (vitamin D, B12, iron) is established clinical medicine, but that is deficiency treatment, not life extension, and evidence for supplementing people who are already replete is largely null or in some trials harmful. Individual components differ sharply in support and should not inherit credibility from the testing wrapped around them. The personalisation itself is the unevidenced claim: measuring a marker, acting on it, and remeasuring demonstrates that the marker moved, not that the patient will live longer or better. Notably, Everlab's own article stresses it does not sell or prescribe named products and matches supplements to test results, which is a more restrained framing than the category norm. Graded commercial because the marketing promise (healthspan extension through a personalised stack) substantially exceeds what the evidence base establishes.

At a glance

Evidence
Commercial
Singapore (HSA)
Health supplements are not pre-approved by HSA. Per HSA, they are not subject to approval or licensing for importation, manufacture or sale, with only voluntary notification; responsibility for safety and compliance sits with the dealer. Products must not contain substances prohibited under the Poisons Act, the Misuse of Drugs Act or the ASEAN negative list, and must meet heavy metal and microbial limits. Critically for this category, HSA states health supplements "must not be labelled, advertised or promoted for any specific medicinal purpose", which bars disease treatment or prevention claims. Note that a clinician prescribing or recommending supplements is a separate matter from the products' own regulatory status.
Australia (TGA)
No TGA position on file
Offered at
3 clinics

Singapore

Health Sciences Authority

HSA status
Health supplements are not pre-approved by HSA. Per HSA, they are not subject to approval or licensing for importation, manufacture or sale, with only voluntary notification; responsibility for safety and compliance sits with the dealer. Products must not contain substances prohibited under the Poisons Act, the Misuse of Drugs Act or the ASEAN negative list, and must meet heavy metal and microbial limits. Critically for this category, HSA states health supplements "must not be labelled, advertised or promoted for any specific medicinal purpose", which bars disease treatment or prevention claims. Note that a clinician prescribing or recommending supplements is a separate matter from the products' own regulatory status.
In our SG set
Tracked in Singapore
SG clinics
None on file

Australia

Therapeutic Goods Administration

TGA status
No position on file
In our AU set
Tracked in Australia
AU clinics
3
Evidence is not approvalAn evidence grade describes how strong the science is. A regulatory status describes whether a body has approved the intervention for an indication. They are different questions, answered separately above.

What it is

Plain-language explainer

A clinic service in which blood and other biomarker testing is used to select a individualised set of supplements, typically corrections for measured deficiencies (vitamin D, B12, iron, omega-3 index) alongside longevity-branded compounds, with repeat testing to track change. It is a bundled process rather than a single product, and what is actually dispensed varies widely between clinics. It is claimed to slow biological ageing or extend healthspan by correcting individual biochemical shortfalls.

Categories

Protocol

Offered by

Where variis has verified this protocol (3)

  • ClinicEverlabMelbourne, Australia
  • ClinicLongevity Medicine Institute (LMI)Sydney, Australia
  • ClinicBespoke LongevityGold Coast, Australia

Common questions

What is Personalised supplement protocol (biomarker-guided stack)?
The bundled offering has no outcome trials. There is no published RCT testing whether biomarker-guided supplement selection, as a strategy, improves mortality, morbidity, or any validated healthspan endpoint versus standard care or versus untargeted supplementation. Correcting a genuine, measured deficiency (vitamin D, B12, iron) is established clinical medicine, but that is deficiency treatment, not life extension, and evidence for supplementing people who are already replete is largely null or in some trials harmful. Individual components differ sharply in support and should not inherit credibility from the testing wrapped around them. The personalisation itself is the unevidenced claim: measuring a marker, acting on it, and remeasuring demonstrates that the marker moved, not that the patient will live longer or better. Notably, Everlab's own article stresses it does not sell or prescribe named products and matches supplements to test results, which is a more restrained framing than the category norm. Graded commercial because the marketing promise (healthspan extension through a personalised stack) substantially exceeds what the evidence base establishes.
How strong is the evidence for Personalised supplement protocol (biomarker-guided stack)?
Commercial. It is offered and sold, which is a statement about availability, not about efficacy.
Is Personalised supplement protocol (biomarker-guided stack) approved in Singapore?
Health Sciences Authority position on record: Health supplements are not pre-approved by HSA. Per HSA, they are not subject to approval or licensing for importation, manufacture or sale, with only voluntary notification; responsibility for safety and compliance sits with the dealer. Products must not contain substances prohibited under the Poisons Act, the Misuse of Drugs Act or the ASEAN negative list, and must meet heavy metal and microbial limits. Critically for this category, HSA states health supplements "must not be labelled, advertised or promoted for any specific medicinal purpose", which bars disease treatment or prevention claims. Note that a clinician prescribing or recommending supplements is a separate matter from the products' own regulatory status.. An evidence grade and a regulatory approval are different questions.
Is Personalised supplement protocol (biomarker-guided stack) approved in Australia?
variis has no Therapeutic Goods Administration position on file for Personalised supplement protocol (biomarker-guided stack). Absence of a recorded position is not approval.
Which clinics offer Personalised supplement protocol (biomarker-guided stack)?
3 clinics in the variis directory across Singapore and Australia have Personalised supplement protocol (biomarker-guided stack) on record. Each is listed on this page with its own sourced profile.
What else is Personalised supplement protocol (biomarker-guided stack) called?
Also known as targeted supplementation, supplement prescription, nutraceutical protocol, biomarker-guided supplementation, personalised stack.

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Sources

What this profile is built on

  1. Regulatory overview of health supplements · Health Sciences Authority (HSA), Singapore
  2. 10 Best Longevity Supplements · Everlab (Australia)
  3. LMI Longevity Medicine protocol page (names no specific drugs) · Longevity Medicine Institute, Double Bay
  4. Bespoke Longevity — clinician approach citing sleep optimisation · Bespoke Longevity

Last updated 14 August 2026

Every entity profile on variis is sourced. Not medical advice.